Purpose : The aim of this study was to investigate the influence of the health information-seeking process on e-health literacy in middle-aged adults. Methods : A secondary data analysis was conducted of publicly available data collected in 2021. A total of 752 adults aged 40 to 64 who had used healthcare services were included. Data on demographic characteristics, health information sources, methods for verifying the reliability of information, and e-health literacy were collected through an online survey. Demographic characteristics included sex, age, marital status, highest education level, subjective health status, and the number of chronic diseases. Health information sources and reliability-checking methods were assessed by having participants select the corresponding responses. e-Health literacy was measured using the 8-item ehealth literacy scale (eHEALS). The data were analyzed using descriptive statistics, the independent t-test, analysis of variance, and multiple regression analyses. Results : Among the 752 participants, 49.9 % were women, and the mean age was 51.46 years. Approximately 75.9 % were married, and 75.1 % held a bachelor’s degree or higher. The average subjective health status was 3.17 out of 5, while the mean e-health literacy score was 29.01 out of 40. The primary sources of health information were credible media and unofficial internet media. The most common method for verifying information reliability was cross-checking multiple news sources and media outlets. Factors that positively influenced e-health literacy included higher subjective health status, the use of unofficial internet media for health information, and verifying information by cross-checking multiple news sources or confirming scientific evidence. Conclusion : The findings indicate a need to manage and monitor the quality of health information on unofficial internet media to enhance e-health literacy among middle-aged adults. They also underscore the importance of promoting reliable methods for assessing the accuracy of health information.